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Diethylcarbamazine citrate

CAS No. 1642-54-2

Diethylcarbamazine citrate( Diethylcarbamazine citrate )

Catalog No. M12496 CAS No. 1642-54-2

Diethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism in filarial microfilaria; is highly specific for several parasites and does not contain any toxic metallic elements.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Diethylcarbamazine citrate
  • Note
    Research use only, not for human use.
  • Brief Description
    Diethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism in filarial microfilaria; is highly specific for several parasites and does not contain any toxic metallic elements.
  • Description
    Diethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism in filarial microfilaria; is highly specific for several parasites and does not contain any toxic metallic elements.
  • In Vitro
    ——
  • In Vivo
    Animal Model:HFD-induced obese mice Dosage:50 mg/kg Administration:p.o.Result:Reduced glucose , triglycerides and insulin levels.Reduced the levels of TNF-α, IL-6 and MCP-1.Reduced COX activity and inhibited this translocated or activated NF-κBp65.
  • Synonyms
    Diethylcarbamazine citrate
  • Pathway
    Chromatin/Epigenetic
  • Target
    COX
  • Recptor
    COX-1| ALOX5
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    1642-54-2
  • Formula Weight
    391.42
  • Molecular Formula
    C10H21N3O·C6H8O7
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 10 mM
  • SMILES
    O=C(N1CCN(C)CC1)N(CC)CC.OC(C(O)=O)(CC(O)=O)CC(O)=O
  • Chemical Name
    N,N-diethyl-4-methylpiperazine-1-carboxamide citrate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Bach MK, Brashler JR. Biochem Pharmacol. 1986 Feb 1;35(3):425-33.
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